A 42-year-old man presents to ENT clinic with a neck lump. He is otherwise asymptomatic. He occasionally drinks alcohol and smokes. The lump is located 7 cm below the right ear lobe, just anterior to the anterior border of the sternocleidomastoid muscle. A biopsy is taken. Pathology results indicate squamous cell carcinoma (SCC) that is p16 positive.
What is the most likely primary site?
- A) Nasopharynx
- B) Oral cavity
- C) Thyroid
- D) Oropharynx
- E) Larynx
ASCENT 